The top-seeded Spartans look to punch their ticket to the Sweet 16 when they face No. 9 Saint Louis in the third round of the NCAA Tournament around 2:45 here at Nationwide Arena in Columbus.
The winner will face Louisville next week at the West Region semifinals in Phoenix.
Michigan State is 16-3 in the second game of a weekend under coach Tom Izzo and are favored to improve that mark to 17-3.
The Billikens finished second in the Atlantic 10 this season and received an at-large bid to the tournament. They defeated No. 8 Memphis on Friday.