Mikel Leshoure punched in a one-yard touchdown run to give the Lions a 14-0 lead with 7:58 left in the first quarter.
But Calvin Johnson has been the story so far. Despite playing on a bad knee, Johnson already has five catches for 99 yards, including a 38-yard catch on third down that put the Lions on the Jacksonville 1.
The Lions are cruising early with 224 total yards. The Jaguars have just eight yards on three drives and have yet to gain a first down.